Dataset Open Access

Data publication: Development and Biological Evaluation of the First Highly Potent and Specific Benzamide-Based Radiotracer [¹⁸F]BA3 for Imaging of Histone Deacetylases 1 and 2 in Brain

Clauß, Oliver; Schäker-Hübner, Linda; Wenzel, Barbara; Toussaint, Magali; Deuther-Conrad, Winnie; Gündel, Daniel; Teodoro, Rodrigo; Dukic-Stefanovic, Sladjana; Ludwig, Friedrich-Alexander; Kopka, Klaus; Brust, Peter; Hansen, Finn K.; Scheunemann, Matthias


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<oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
  <dc:creator>Clauß, Oliver</dc:creator>
  <dc:creator>Schäker-Hübner, Linda</dc:creator>
  <dc:creator>Wenzel, Barbara</dc:creator>
  <dc:creator>Toussaint, Magali</dc:creator>
  <dc:creator>Deuther-Conrad, Winnie</dc:creator>
  <dc:creator>Gündel, Daniel</dc:creator>
  <dc:creator>Teodoro, Rodrigo</dc:creator>
  <dc:creator>Dukic-Stefanovic, Sladjana</dc:creator>
  <dc:creator>Ludwig, Friedrich-Alexander</dc:creator>
  <dc:creator>Kopka, Klaus</dc:creator>
  <dc:creator>Brust, Peter</dc:creator>
  <dc:creator>Hansen, Finn K.</dc:creator>
  <dc:creator>Scheunemann, Matthias</dc:creator>
  <dc:date>2022-03-10</dc:date>
  <dc:description>The data publication contain: 1) Radiosynthesis data (Scheme of the synthesis module; RP-HPLC chromatograms of formulated [18F]BA3; MLC chromatograms of in vivo metabolism studies) 2) Biological data (Baseline TAC of CD-1 mice brain, biodistribution after i.v. injection of [18F]BA3) 3) Analytical data (1H, 13C, 19F NMR spectra; LC-MS chromatograms for final products)</dc:description>
  <dc:identifier>https://rodare.hzdr.de/record/1507</dc:identifier>
  <dc:identifier>10.14278/rodare.1507</dc:identifier>
  <dc:identifier>oai:rodare.hzdr.de:1507</dc:identifier>
  <dc:relation>url:https://www.hzdr.de/publications/Publ-34169</dc:relation>
  <dc:relation>url:https://www.hzdr.de/publications/Publ-34366</dc:relation>
  <dc:relation>doi:10.3390/ph15030324</dc:relation>
  <dc:relation>doi:10.14278/rodare.1474</dc:relation>
  <dc:relation>url:https://rodare.hzdr.de/communities/rodare</dc:relation>
  <dc:rights>info:eu-repo/semantics/openAccess</dc:rights>
  <dc:rights>https://creativecommons.org/licenses/by/4.0/legalcode</dc:rights>
  <dc:subject>histone deacetylase inhibitor</dc:subject>
  <dc:subject>HDAC1/2-specific</dc:subject>
  <dc:subject>radiochemistry</dc:subject>
  <dc:subject>fluorine-18 labelling</dc:subject>
  <dc:subject>positron emission tomography (PET)</dc:subject>
  <dc:subject>brain-penetration</dc:subject>
  <dc:subject>glioblastoma</dc:subject>
  <dc:subject>glioma</dc:subject>
  <dc:title>Data publication: Development and Biological Evaluation of the First Highly Potent and Specific Benzamide-Based Radiotracer [¹⁸F]BA3 for Imaging of Histone Deacetylases 1 and 2 in Brain</dc:title>
  <dc:type>info:eu-repo/semantics/other</dc:type>
  <dc:type>dataset</dc:type>
</oai_dc:dc>
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