Dataset Open Access
Clauß, Oliver; Schäker-Hübner, Linda; Wenzel, Barbara; Toussaint, Magali; Deuther-Conrad, Winnie; Gündel, Daniel; Teodoro, Rodrigo; Dukic-Stefanovic, Sladjana; Ludwig, Friedrich-Alexander; Kopka, Klaus; Brust, Peter; Hansen, Finn K.; Scheunemann, Matthias
{ "description": "<p>The data publication contain: 1) Radiosynthesis data (Scheme of the synthesis module; RP-HPLC chromatograms of formulated [18F]BA3; MLC chromatograms of in vivo metabolism studies) 2) Biological data (Baseline TAC of CD-1 mice brain, biodistribution after i.v. injection of [18F]BA3) 3) Analytical data (1H, 13C, 19F NMR spectra; LC-MS chromatograms for final products)</p>", "sameAs": [ "https://www.hzdr.de/publications/Publ-34366" ], "datePublished": "2022-03-10", "@type": "Dataset", "distribution": [ { "contentUrl": "https://rodare.hzdr.de/api/files/f1581191-e1b8-48c2-9157-d3416403bbea/Clau\u00df_Scheunemann_Development_Biological_Evaluation_Benzamide-Based_Radiotracer_HDAC1_2_Brain_Pharmaceuticals_2022_15_324_SI.pdf", "fileFormat": "pdf", "@type": "DataDownload" }, { "contentUrl": "https://rodare.hzdr.de/api/files/f1581191-e1b8-48c2-9157-d3416403bbea/Data.zip", "fileFormat": "zip", "@type": "DataDownload" } ], "keywords": [ "histone deacetylase inhibitor", "HDAC1/2-specific", "radiochemistry", "fluorine-18 labelling", "positron emission tomography (PET)", "brain-penetration", "glioblastoma", "glioma" ], "@context": "https://schema.org/", "@id": "https://doi.org/10.14278/rodare.1507", "creator": [ { "name": "Clau\u00df, Oliver", "@id": "https://orcid.org/0000-0001-5067-4845", "@type": "Person" }, { "name": "Sch\u00e4ker-H\u00fcbner, Linda", "affiliation": "Universit\u00e4t Bonn", "@type": "Person" }, { "name": "Wenzel, Barbara", "@id": "https://orcid.org/0000-0001-7390-3575", "@type": "Person" }, { "name": "Toussaint, Magali", "@id": "https://orcid.org/0000-0002-1136-3857", "@type": "Person" }, { "name": "Deuther-Conrad, Winnie", "@id": "https://orcid.org/0000-0003-3168-3062", "@type": "Person" }, { "name": "G\u00fcndel, Daniel", "@id": "https://orcid.org/0000-0001-9743-2325", "@type": "Person" }, { "name": "Teodoro, Rodrigo", "@id": "https://orcid.org/0000-0002-1425-0567", "@type": "Person" }, { "name": "Dukic-Stefanovic, Sladjana", "@type": "Person" }, { "name": "Ludwig, Friedrich-Alexander", "@id": "https://orcid.org/0000-0002-4358-5171", "@type": "Person" }, { "name": "Kopka, Klaus", "@id": "https://orcid.org/0000-0003-4846-1271", "@type": "Person" }, { "name": "Brust, Peter", "@id": "https://orcid.org/0000-0001-5555-7058", "@type": "Person" }, { "name": "Hansen, Finn K.", "@id": "https://orcid.org/0000-0001-9765-5975", "affiliation": "Universit\u00e4t Bonn", "@type": "Person" }, { "name": "Scheunemann, Matthias", "@type": "Person" } ], "url": "https://rodare.hzdr.de/record/1507", "identifier": "https://doi.org/10.14278/rodare.1507", "name": "Data publication: Development and Biological Evaluation of the First Highly Potent and Specific Benzamide-Based Radiotracer [\u00b9\u2078F]BA3 for Imaging of Histone Deacetylases 1 and 2 in Brain", "license": "https://creativecommons.org/licenses/by/4.0/legalcode" }
All versions | This version | |
---|---|---|
Views | 842 | 329 |
Downloads | 276 | 218 |
Data volume | 1.6 GB | 1.1 GB |
Unique views | 275 | 129 |
Unique downloads | 118 | 72 |