Dataset Open Access
Data publication: Development and Biological Evaluation of the First Highly Potent and Specific Benzamide-Based Radiotracer [¹⁸F]BA3 for Imaging of Histone Deacetylases 1 and 2 in Brain
Clauß, Oliver;
Schäker-Hübner, Linda;
Wenzel, Barbara;
Toussaint, Magali;
Deuther-Conrad, Winnie;
Gündel, Daniel;
Teodoro, Rodrigo;
Dukic-Stefanovic, Sladjana;
Ludwig, Friedrich-Alexander;
Kopka, Klaus;
Brust, Peter;
Hansen, Finn K.;
Scheunemann, Matthias
The data publication contain: 1) Radiosynthesis data (Scheme of the synthesis module; RP-HPLC chromatograms of formulated [18F]BA3; MLC chromatograms of in vivo metabolism studies) 2) Biological data (Baseline TAC of CD-1 mice brain, biodistribution after i.v. injection of [18F]BA3) 3) Analytical data (1H, 13C, 19F NMR spectra; LC-MS chromatograms for final products)
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|---|---|---|
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Clauß_Scheunemann_Development_Biological_Evaluation_Benzamide-Based_Radiotracer_HDAC1_2_Brain_Pharmaceuticals_2022_15_324_SI.pdf
md5:a79d0c5b8f86d3245ffb83767be75166 |
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| Data volume | 1.6 GB | 509.9 MB |
| Unique views | 275 | 163 |
| Unique downloads | 118 | 47 |
- Publication date:
- March 10, 2022
- DOI:
-
- Keyword(s):
- histone deacetylase inhibitor HDAC1/2-specific radiochemistry fluorine-18 labelling positron emission tomography (PET) brain-penetration glioblastoma glioma
- Related identifiers:
- Identical to:
https://www.hzdr.de/publications/Publ-34366 - Referenced by:
https://www.hzdr.de/publications/Publ-34169, 10.3390/ph15030324 - Communities:
- License (for files):
- Creative Commons Attribution 4.0 International