December 1, 2025 Dataset Open Access

Arndt, Philipp; Morton, Lorena; Briese, Michael; Lämmlin, Naomi; Mattern, Hendrik; Hasanuzzaman, Md.; Westhues, Melina; Khoshneviszadeh, Mahsima; Appenzeller, Silke; Gündel, Daniel; Toussaint, Magali; Brust, Peter; Knieß, Torsten; Oelschlegel, Anja; Goldschmidt, Jürgen; Meuth, Sven; Müller, Patrick; Braun‐Dullaeus, Rüdiger; Debska‐Vielhaber, Grazyna; Vielhaber, Stefan; Becker, Axel; Dityatev, Alexander; Henneicke, Solveig; Sendtner, Michael; Dunay, Ildiko; Schreiber, Stefanie

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{
  "@type": "Dataset", 
  "license": "https://creativecommons.org/licenses/by/4.0/legalcode", 
  "url": "https://rodare.hzdr.de/record/4168", 
  "creator": [
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      "@type": "Person", 
      "name": "Arndt, Philipp", 
      "affiliation": "Department of Neurology, Otto-\u00advon-\u00adGuericke 2. Palta P, Albert MS, Gottesman RF. Heart health meets cognitive health: evidence on the role of blood pressure. Lancet Neurol. 2021;20:854\u2013 867. doi: 10.1016/S1474-\u00ad4422(21)00248-\u00ad9 3. Iadecola C, Duering M, Hachinski V, Joutel A, Pendlebury ST, Schneider JA, Dichgans M. Vascular cognitive impairment and dementia. J Am Coll Cardiol. 2019;73:3326\u20133344. doi: 10.1016/j.jacc.2019.04.034 4. Cai Z, Wang C, He W, Tu H, Tang Z, Xiao M, Yan L-\u00adJ. Cerebral sm"
    }, 
    {
      "@type": "Person", 
      "name": "Morton, Lorena", 
      "affiliation": "Institute of Inflammation and Neurodegeneration, Otto-\u00advon-\u00adGuericke University, Magdeburg"
    }, 
    {
      "@type": "Person", 
      "name": "Briese, Michael", 
      "affiliation": "Institute of Clinical Neurobiology, University Hospital W\u00fcrzburg, W\u00fcrzburg"
    }, 
    {
      "@type": "Person", 
      "name": "L\u00e4mmlin, Naomi", 
      "affiliation": "Department of Neurology, University Hospital Leipzig, Leipzig"
    }, 
    {
      "@type": "Person", 
      "name": "Mattern, Hendrik", 
      "affiliation": "German Center for Neurodegenerative Diseases (DZNE) within the Helmholtz Association, Magdeburg"
    }, 
    {
      "@type": "Person", 
      "name": "Hasanuzzaman, Md.", 
      "affiliation": "Department of Neurology, Otto-\u00advon-\u00adGuericke 2. Palta P, Albert MS, Gottesman RF. Heart health meets cognitive health: evidence on the role of blood pressure. Lancet Neurol. 2021;20:854\u2013 867. doi: 10.1016/S1474-\u00ad4422(21)00248-\u00ad9 3. Iadecola C, Duering M, Hachinski V, Joutel A, Pendlebury ST, Schneider JA, Dichgans M. Vascular cognitive impairment and dementia. J Am Coll Cardiol. 2019;73:3326\u20133344. doi: 10.1016/j.jacc.2019.04.034 4. Cai Z, Wang C, He W, Tu H, Tang Z, Xiao M, Yan L-\u00adJ. Cerebral sm"
    }, 
    {
      "@type": "Person", 
      "name": "Westhues, Melina", 
      "affiliation": "Department of Neurology, Otto-\u00advon-\u00adGuericke 2. Palta P, Albert MS, Gottesman RF. Heart health meets cognitive health: evidence on the role of blood pressure. Lancet Neurol. 2021;20:854\u2013 867. doi: 10.1016/S1474-\u00ad4422(21)00248-\u00ad9 3. Iadecola C, Duering M, Hachinski V, Joutel A, Pendlebury ST, Schneider JA, Dichgans M. Vascular cognitive impairment and dementia. J Am Coll Cardiol. 2019;73:3326\u20133344. doi: 10.1016/j.jacc.2019.04.034 4. Cai Z, Wang C, He W, Tu H, Tang Z, Xiao M, Yan L-\u00adJ. Cerebral sm"
    }, 
    {
      "@type": "Person", 
      "name": "Khoshneviszadeh, Mahsima", 
      "affiliation": "Department of Neurology, Otto-\u00advon-\u00adGuericke 2. Palta P, Albert MS, Gottesman RF. Heart health meets cognitive health: evidence on the role of blood pressure. Lancet Neurol. 2021;20:854\u2013 867. doi: 10.1016/S1474-\u00ad4422(21)00248-\u00ad9 3. Iadecola C, Duering M, Hachinski V, Joutel A, Pendlebury ST, Schneider JA, Dichgans M. Vascular cognitive impairment and dementia. J Am Coll Cardiol. 2019;73:3326\u20133344. doi: 10.1016/j.jacc.2019.04.034 4. Cai Z, Wang C, He W, Tu H, Tang Z, Xiao M, Yan L-\u00adJ. Cerebral sm"
    }, 
    {
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      "name": "Appenzeller, Silke", 
      "affiliation": "Comprehensive Cancer Center Mainfranken, University Hospital W\u00fcrzburg, W\u00fcrzburg"
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    {
      "@type": "Person", 
      "name": "G\u00fcndel, Daniel", 
      "@id": "https://orcid.org/0000-0001-9743-2325"
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    {
      "@type": "Person", 
      "name": "Toussaint, Magali", 
      "@id": "https://orcid.org/0000-0002-1136-3857"
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      "name": "Brust, Peter", 
      "@id": "https://orcid.org/0000-0001-5555-7058"
    }, 
    {
      "@type": "Person", 
      "name": "Knie\u00df, Torsten", 
      "@id": "https://orcid.org/0000-0002-4107-3455"
    }, 
    {
      "@type": "Person", 
      "name": "Oelschlegel, Anja", 
      "affiliation": "Leibniz-\u00adInstitute for Neurobiology, Magdeburg"
    }, 
    {
      "@type": "Person", 
      "name": "Goldschmidt, J\u00fcrgen", 
      "affiliation": "Leibniz-\u00adInstitute for Neurobiology, Magdeburg"
    }, 
    {
      "@type": "Person", 
      "name": "Meuth, Sven", 
      "affiliation": "Department of Neurology, Heinrich-\u00adHeine-\u00adUniversity, D\u00fcsseldorf"
    }, 
    {
      "@type": "Person", 
      "name": "M\u00fcller, Patrick", 
      "affiliation": "Department of Cardiology, Otto-\u00advon-\u00adGuericke University, Magdeburg"
    }, 
    {
      "@type": "Person", 
      "name": "Braun\u2010Dullaeus, R\u00fcdiger", 
      "affiliation": "Department of Cardiology, Otto-\u00advon-\u00adGuericke University, Magdeburg"
    }, 
    {
      "@type": "Person", 
      "name": "Debska\u2010Vielhaber, Grazyna", 
      "affiliation": "Department of Neurology, Otto-\u00advon-\u00adGuericke 2. Palta P, Albert MS, Gottesman RF. Heart health meets cognitive health: evidence on the role of blood pressure. Lancet Neurol. 2021;20:854\u2013 867. doi: 10.1016/S1474-\u00ad4422(21)00248-\u00ad9 3. Iadecola C, Duering M, Hachinski V, Joutel A, Pendlebury ST, Schneider JA, Dichgans M. Vascular cognitive impairment and dementia. J Am Coll Cardiol. 2019;73:3326\u20133344. doi: 10.1016/j.jacc.2019.04.034 4. Cai Z, Wang C, He W, Tu H, Tang Z, Xiao M, Yan L-\u00adJ. Cerebral sm"
    }, 
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      "@type": "Person", 
      "name": "Vielhaber, Stefan", 
      "affiliation": "Department of Neurology, Otto-\u00advon-\u00adGuericke 2. Palta P, Albert MS, Gottesman RF. Heart health meets cognitive health: evidence on the role of blood pressure. Lancet Neurol. 2021;20:854\u2013 867. doi: 10.1016/S1474-\u00ad4422(21)00248-\u00ad9 3. Iadecola C, Duering M, Hachinski V, Joutel A, Pendlebury ST, Schneider JA, Dichgans M. Vascular cognitive impairment and dementia. J Am Coll Cardiol. 2019;73:3326\u20133344. doi: 10.1016/j.jacc.2019.04.034 4. Cai Z, Wang C, He W, Tu H, Tang Z, Xiao M, Yan L-\u00adJ. Cerebral sm"
    }, 
    {
      "@type": "Person", 
      "name": "Becker, Axel", 
      "affiliation": "Institute of Pharmacology and Toxicology, Otto-\u00advon-\u00adGuericke University, Magdeburg, Germany"
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      "@type": "Person", 
      "name": "Dityatev, Alexander", 
      "affiliation": "German Center for Neurodegenerative Diseases (DZNE) within the Helmholtz Association, Magdeburg"
    }, 
    {
      "@type": "Person", 
      "name": "Henneicke, Solveig", 
      "affiliation": "Department of Neurology, Otto-\u00advon-\u00adGuericke 2. Palta P, Albert MS, Gottesman RF. Heart health meets cognitive health: evidence on the role of blood pressure. Lancet Neurol. 2021;20:854\u2013 867. doi: 10.1016/S1474-\u00ad4422(21)00248-\u00ad9 3. Iadecola C, Duering M, Hachinski V, Joutel A, Pendlebury ST, Schneider JA, Dichgans M. Vascular cognitive impairment and dementia. J Am Coll Cardiol. 2019;73:3326\u20133344. doi: 10.1016/j.jacc.2019.04.034 4. Cai Z, Wang C, He W, Tu H, Tang Z, Xiao M, Yan L-\u00adJ. Cerebral sm"
    }, 
    {
      "@type": "Person", 
      "name": "Sendtner, Michael", 
      "affiliation": "Institute of Clinical Neurobiology, University Hospital W\u00fcrzburg, W\u00fcrzburg"
    }, 
    {
      "@type": "Person", 
      "name": "Dunay, Ildiko", 
      "affiliation": "Institute of Inflammation and Neurodegeneration, Otto-\u00advon-\u00adGuericke University, Magdeburg"
    }, 
    {
      "@type": "Person", 
      "name": "Schreiber, Stefanie", 
      "affiliation": "Department of Neurology, Otto-\u00advon-\u00adGuericke 2. Palta P, Albert MS, Gottesman RF. Heart health meets cognitive health: evidence on the role of blood pressure. Lancet Neurol. 2021;20:854\u2013 867. doi: 10.1016/S1474-\u00ad4422(21)00248-\u00ad9 3. Iadecola C, Duering M, Hachinski V, Joutel A, Pendlebury ST, Schneider JA, Dichgans M. Vascular cognitive impairment and dementia. J Am Coll Cardiol. 2019;73:3326\u20133344. doi: 10.1016/j.jacc.2019.04.034 4. Cai Z, Wang C, He W, Tu H, Tang Z, Xiao M, Yan L-\u00adJ. Cerebral sm"
    }
  ], 
  "datePublished": "2025-12-01", 
  "identifier": "https://doi.org/10.14278/rodare.4168", 
  "@context": "https://schema.org/", 
  "description": "<p>datasheet animals (rats) for FDG-PET and DICOMS of PET aquisitions</p>", 
  "name": "Data publication: Vascular and Neural Transcriptomics Reveal Stage\u2010Dependent Pathways to Inflammation and Cognitive Dysfunction in a Rat Model of Hypertension", 
  "@id": "https://doi.org/10.14278/rodare.4168", 
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      "contentUrl": "https://rodare.hzdr.de/api/files/98a646e3-4d10-4216-abfc-8060e468ac7c/Magdeburg_rat_PET.xlsx"
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      "contentUrl": "https://rodare.hzdr.de/api/files/98a646e3-4d10-4216-abfc-8060e468ac7c/SHSRP.zip"
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  ], 
  "keywords": [
    "18F-\u00adFDG PET", 
    "cerebral small-\u00advessel disease", 
    "hypertension", 
    "RNA sequencing", 
    "SHRSP"
  ]
}