September 18, 2024 Dataset Open Access

Gündel, Daniel; Teodoro, Rodrigo; Ludwig, Friedrich-Alexander; Heerklotz, Anne; Toussaint, Magali; Deuther-Conrad, Winnie; Bormans, Guy; Brust, Peter; Kopka, Klaus; Moldovan, Rares-Petru

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    "description": "<p>What is already known \u2022 Increased expression of the CB2R in the brain is linked to certain neuropathological diseases. \u2022 First clinical trials for CB2R-directed therapies are conducted. What this study adds \u2022 [18F]JHU94620-d8 provides the potential to quantify the CB2R receptor density in the brain by positron-emission-tomography. Clinical significance \u2022 Stratification of patients for CB2R-directed therapies and follow up of the treatment response is needed.</p>", 
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    "title": "Data publication: Development and Evaluation of Deuterated [18F]JHU94620 Isotopologues for the Non-invasive Assessment of the Cannabinoid type 2 Receptor in Brain"
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