Dataset Open Access

Data publication: Development and Evaluation of Deuterated [18F]JHU94620 Isotopologues for the Non-invasive Assessment of the Cannabinoid type 2 Receptor in Brain

Gündel, Daniel; Teodoro, Rodrigo; c, Friedrich-Alexander Ludwig a.; Heerklotz a., Anne; Toussaint, Magali; Deuther-Conrad, Winnie; Bormans d., Guy; Brust a., Peter; Kopka, Klaus; Moldovan, Rares-Petru; f, Rareş-Petru Moldovan

What is already known • Increased expression of the CB2R in the brain is linked to certain neuropathological diseases. • First clinical trials for CB2R-directed therapies are conducted. What this study adds • [18F]JHU94620-d8 provides the potential to quantify the CB2R receptor density in the brain by positron-emission-tomography. Clinical significance • Stratification of patients for CB2R-directed therapies and follow up of the treatment response is needed.

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