Dataset Open Access
Slice2Volume: Fusion of multimodal medical imaging and light microscopy data of irradiation-injured brain tissue in 3D.
Müller, Johannes;
Suckert, Theresa;
Beyreuther, Elke;
Schneider, Moritz;
Boucsein, Marc;
Bodenstein, Elisabeth;
Stolz-Kieslich, Liane;
Krause, Mechthild;
von Neubeck, Cläre;
Haase, Robert;
Lühr, Armin;
Dietrich, Antje
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"description": "<p>The dataset contains comprehensive image data for a total of nine mice, which underwent normal tissue brain irradiation with 90 MeV protons. <br>\nIn particular, the image data comprise cone-bem computed tomographies (CBCT), Monte Carlo beam transport simulations based on those CTs, regular magnetic resonance imaging (MRI) follow-up (≥ 26 weeks), a co-aligned DSURQE mouse brain atlas and scanned whole-brain tissue sections with histochemical and immunofluorescent markers for morphology (H&E), cell nuclei (DAPI), astrocytes (GFAP), microglia (Iba1), the intermediate filament protein Nestin, proliferation (Ki67), neurons (NeuN) and oligodendrocytes (OSP). <br>\nThe volumetric image data (i.e. CBCT, MRI and brain atlas) were co-aligned using the ImageJ plugin Big Warp. The CBCT data was used as spatial reference to allow for mask-based, slice-wise alignment of CBCT and light microscopy image data in 3D with the scriptable registration tool Elastix. </p>\n\n<p>We provide the data in raw format and as aligned data sets, as well as their spatial transformations.</p>",
"doi": "10.14278/rodare.915",
"access_right_category": "success",
"version": "0.3.1",
"publication_date": "2021-01-20",
"title": "Slice2Volume: Fusion of multimodal medical imaging and light microscopy data of irradiation-injured brain tissue in 3D.",
"doc_id": "1",
"pub_id": "32124",
"license": {
"id": "CC-BY-4.0"
}
},
"doi": "10.14278/rodare.915",
"conceptrecid": "557",
"owners": [
416
],
"revision": 13,
"updated": "2023-05-30T13:11:26.447722+00:00",
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"conceptdoi": "10.14278/rodare.557",
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9,790
67,206
views
downloads
| All versions | This version | |
|---|---|---|
| Views | 9,790 | 2,333 |
| Downloads | 67,206 | 18,457 |
| Data volume | 832.7 TB | 237.9 TB |
| Unique views | 5,688 | 1,735 |
| Unique downloads | 28,991 | 11,256 |
- Publication date:
- January 20, 2021
- DOI:
-
- Keyword(s):
- Preclinical Image fusion Proton radiation Medical imaging Histology
- Grants:
-
European Commission:
- INSPIRE - INfraStructure in Proton International REsearch (730983)
- Related identifiers:
- Identical to:
https://www.hzdr.de/publications/Publ-32124 - Referenced by:
https://www.hzdr.de/publications/Publ-31469 - Communities:
- License (for files):
- Creative Commons Attribution 4.0 International
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Cite as
Müller, Johannes, Suckert, Theresa, Beyreuther, Elke, Schneider, Moritz, Boucsein, Marc, Bodenstein, Elisabeth, … Dietrich, Antje. (2021). Slice2Volume: Fusion of multimodal medical imaging and light microscopy data of irradiation-injured brain tissue in 3D. (Version 0.3.1) [Data set]. Rodare. http://doi.org/10.14278/rodare.915
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