Dataset Open Access

Data publication: Structural and Electronic Impact of Chelators on Immunoconjugates

Kennedy, Adam. C.; Anger, Karl; Neuber, Christin; Neupert, Lucca; Cieslik, Patrick Arthur; Gast, Michael; Feldmann, Anja; Bachmann, Michael; Pietzsch, Jens; Stephan, Holger; Comba, Peter; Kubeil, Manja

JSON Export

{
  "links": {
    "badge": "https://rodare.hzdr.de/badge/doi/10.14278/rodare.4993.svg", 
    "doi": "https://doi.org/10.14278/rodare.4993", 
    "conceptbadge": "https://rodare.hzdr.de/badge/doi/10.14278/rodare.4992.svg", 
    "conceptdoi": "https://doi.org/10.14278/rodare.4992", 
    "bucket": "https://rodare.hzdr.de/api/files/578725c9-1f4e-4ef3-8385-5ff8181142e2", 
    "html": "https://rodare.hzdr.de/record/4993", 
    "latest": "https://rodare.hzdr.de/api/records/4993", 
    "latest_html": "https://rodare.hzdr.de/record/4993"
  }, 
  "updated": "2026-09-07T06:20:49.119521+00:00", 
  "stats": {
    "volume": 355211.0, 
    "unique_downloads": 1.0, 
    "version_unique_downloads": 1.0, 
    "unique_views": 1.0, 
    "downloads": 1.0, 
    "version_unique_views": 1.0, 
    "version_views": 1.0, 
    "version_downloads": 1.0, 
    "version_volume": 355211.0, 
    "views": 1.0
  }, 
  "owners": [
    682
  ], 
  "id": 4993, 
  "metadata": {
    "access_right": "open", 
    "license": {
      "id": "CC-BY-4.0"
    }, 
    "creators": [
      {
        "affiliation": "Monash University", 
        "name": "Kennedy, Adam. C."
      }, 
      {
        "orcid": "0009-0005-3638-0951", 
        "name": "Anger, Karl"
      }, 
      {
        "orcid": "0000-0002-0646-5808", 
        "name": "Neuber, Christin"
      }, 
      {
        "affiliation": "Universit\u00e4t Heidelberg", 
        "name": "Neupert, Lucca"
      }, 
      {
        "name": "Cieslik, Patrick Arthur"
      }, 
      {
        "affiliation": "niversit\u00e4t Heidelberg", 
        "name": "Gast, Michael"
      }, 
      {
        "orcid": "0000-0001-5099-2448", 
        "name": "Feldmann, Anja"
      }, 
      {
        "name": "Bachmann, Michael"
      }, 
      {
        "orcid": "0000-0002-1610-1493", 
        "name": "Pietzsch, Jens"
      }, 
      {
        "orcid": "0000-0002-2972-2803", 
        "name": "Stephan, Holger"
      }, 
      {
        "affiliation": "Universit\u00e4t Heidelberg", 
        "name": "Comba, Peter"
      }, 
      {
        "orcid": "0000-0001-8857-5922", 
        "name": "Kubeil, Manja"
      }
    ], 
    "doi": "10.14278/rodare.4993", 
    "publication_date": "2026-09-03", 
    "keywords": [
      "bispidine chelators", 
      "copper-64", 
      "radioimmunoconjugate", 
      "fibroblast activation protein", 
      "positron emission tomography"
    ], 
    "relations": {
      "version": [
        {
          "parent": {
            "pid_value": "4992", 
            "pid_type": "recid"
          }, 
          "is_last": true, 
          "index": 0, 
          "last_child": {
            "pid_value": "4993", 
            "pid_type": "recid"
          }, 
          "count": 1
        }
      ]
    }, 
    "communities": [
      {
        "id": "health"
      }, 
      {
        "id": "rodare"
      }
    ], 
    "pub_id": "43869", 
    "title": "Data publication: Structural and Electronic Impact of Chelators on Immunoconjugates", 
    "resource_type": {
      "type": "dataset", 
      "title": "Dataset"
    }, 
    "related_identifiers": [
      {
        "scheme": "url", 
        "relation": "isIdenticalTo", 
        "identifier": "https://www.hzdr.de/publications/Publ-43869"
      }, 
      {
        "scheme": "url", 
        "relation": "isReferencedBy", 
        "identifier": "https://www.hzdr.de/publications/Publ-43868"
      }, 
      {
        "scheme": "doi", 
        "relation": "isVersionOf", 
        "identifier": "10.14278/rodare.4992"
      }
    ], 
    "doc_id": "1", 
    "description": "<p>the following data are available: MS spectra of chelator L3 and its derivatives as well as their respective immunoconjugates,&nbsp;in vitro binding studies</p>", 
    "access_right_category": "success"
  }, 
  "files": [
    {
      "key": "01_analytical_RP-HPLC_chromtogram_(L3)2-_after_purification_254nm.txt", 
      "size": 734481, 
      "links": {
        "self": "https://rodare.hzdr.de/api/files/578725c9-1f4e-4ef3-8385-5ff8181142e2/01_analytical_RP-HPLC_chromtogram_%28L3%292-_after_purification_254nm.txt"
      }, 
      "bucket": "578725c9-1f4e-4ef3-8385-5ff8181142e2", 
      "type": "txt", 
      "checksum": "md5:6dd990c99ce15b6a0e868d5edeff9c89"
    }, 
    {
      "key": "01_HRMS_analysis_report_Cu(II)-L3.pdf", 
      "size": 355211, 
      "links": {
        "self": "https://rodare.hzdr.de/api/files/578725c9-1f4e-4ef3-8385-5ff8181142e2/01_HRMS_analysis_report_Cu%28II%29-L3.pdf"
      }, 
      "bucket": "578725c9-1f4e-4ef3-8385-5ff8181142e2", 
      "type": "pdf", 
      "checksum": "md5:03505f096ce74dcceb23754a9d08320e"
    }, 
    {
      "key": "01_SEC-chromatogram_L1-anti-FAP-TM_after_purification.xlsx", 
      "size": 69391, 
      "links": {
        "self": "https://rodare.hzdr.de/api/files/578725c9-1f4e-4ef3-8385-5ff8181142e2/01_SEC-chromatogram_L1-anti-FAP-TM_after_purification.xlsx"
      }, 
      "bucket": "578725c9-1f4e-4ef3-8385-5ff8181142e2", 
      "type": "xlsx", 
      "checksum": "md5:9d2df31559883c7f2cbdd408fbe7d8ff"
    }, 
    {
      "key": "02_HRMS_analyis_report_tBu-L3-pBnNCS.pdf", 
      "size": 286209, 
      "links": {
        "self": "https://rodare.hzdr.de/api/files/578725c9-1f4e-4ef3-8385-5ff8181142e2/02_HRMS_analyis_report_tBu-L3-pBnNCS.pdf"
      }, 
      "bucket": "578725c9-1f4e-4ef3-8385-5ff8181142e2", 
      "type": "pdf", 
      "checksum": "md5:86811bb4ef2e8d1c513f8fdc66b742ad"
    }, 
    {
      "key": "02-SEC-chromatogram_L3-anti-FAP-TM_after_purification.xlsx", 
      "size": 69928, 
      "links": {
        "self": "https://rodare.hzdr.de/api/files/578725c9-1f4e-4ef3-8385-5ff8181142e2/02-SEC-chromatogram_L3-anti-FAP-TM_after_purification.xlsx"
      }, 
      "bucket": "578725c9-1f4e-4ef3-8385-5ff8181142e2", 
      "type": "xlsx", 
      "checksum": "md5:b1b3f624d0749b7a74eff2898c857dc3"
    }, 
    {
      "key": "03_HRMS_analysis_report_tBu-L3-pBnNH2.pdf", 
      "size": 253270, 
      "links": {
        "self": "https://rodare.hzdr.de/api/files/578725c9-1f4e-4ef3-8385-5ff8181142e2/03_HRMS_analysis_report_tBu-L3-pBnNH2.pdf"
      }, 
      "bucket": "578725c9-1f4e-4ef3-8385-5ff8181142e2", 
      "type": "pdf", 
      "checksum": "md5:193cb138187ab936b7f0628930a2d420"
    }, 
    {
      "key": "03_radio-SEC-chromatogram_64Cu-L1-anti-FAP-TM.xlsx", 
      "size": 322001, 
      "links": {
        "self": "https://rodare.hzdr.de/api/files/578725c9-1f4e-4ef3-8385-5ff8181142e2/03_radio-SEC-chromatogram_64Cu-L1-anti-FAP-TM.xlsx"
      }, 
      "bucket": "578725c9-1f4e-4ef3-8385-5ff8181142e2", 
      "type": "xlsx", 
      "checksum": "md5:f147c15dae980e7a3a726fab8b8cd028"
    }, 
    {
      "key": "04-HRMS_analysis_report_tBu-L3-pBnNO2.pdf", 
      "size": 202548, 
      "links": {
        "self": "https://rodare.hzdr.de/api/files/578725c9-1f4e-4ef3-8385-5ff8181142e2/04-HRMS_analysis_report_tBu-L3-pBnNO2.pdf"
      }, 
      "bucket": "578725c9-1f4e-4ef3-8385-5ff8181142e2", 
      "type": "pdf", 
      "checksum": "md5:7cde71f3798e8ad2599bd6119467e4e7"
    }, 
    {
      "key": "04_radio-SEC-chromatogram_64Cu-L3-anti-FAP-TM.xlsx", 
      "size": 726217, 
      "links": {
        "self": "https://rodare.hzdr.de/api/files/578725c9-1f4e-4ef3-8385-5ff8181142e2/04_radio-SEC-chromatogram_64Cu-L3-anti-FAP-TM.xlsx"
      }, 
      "bucket": "578725c9-1f4e-4ef3-8385-5ff8181142e2", 
      "type": "xlsx", 
      "checksum": "md5:d337936aacd1be6d5f4276fdf439bf46"
    }, 
    {
      "key": "05_HRMS_analysis_report_(L3)2-.pdf", 
      "size": 299702, 
      "links": {
        "self": "https://rodare.hzdr.de/api/files/578725c9-1f4e-4ef3-8385-5ff8181142e2/05_HRMS_analysis_report_%28L3%292-.pdf"
      }, 
      "bucket": "578725c9-1f4e-4ef3-8385-5ff8181142e2", 
      "type": "pdf", 
      "checksum": "md5:24a54786676a9458b15ff153a8e6ced2"
    }, 
    {
      "key": "05_radio-SEC-chromatogram_64Cu-L1-anti-FAP-TM_urine_1h.xlsx", 
      "size": 400537, 
      "links": {
        "self": "https://rodare.hzdr.de/api/files/578725c9-1f4e-4ef3-8385-5ff8181142e2/05_radio-SEC-chromatogram_64Cu-L1-anti-FAP-TM_urine_1h.xlsx"
      }, 
      "bucket": "578725c9-1f4e-4ef3-8385-5ff8181142e2", 
      "type": "xlsx", 
      "checksum": "md5:aa4609372ae7d86e484753dbfd761073"
    }, 
    {
      "key": "06_HRMS_analysis_report_tBu-L3.pdf", 
      "size": 252592, 
      "links": {
        "self": "https://rodare.hzdr.de/api/files/578725c9-1f4e-4ef3-8385-5ff8181142e2/06_HRMS_analysis_report_tBu-L3.pdf"
      }, 
      "bucket": "578725c9-1f4e-4ef3-8385-5ff8181142e2", 
      "type": "pdf", 
      "checksum": "md5:e83ba3ecb31055afe2a5af98a634c975"
    }, 
    {
      "key": "06_ radio-SEC-chromatogram_64Cu-L3-anti-FAP-TM_urine_1h.xlsx", 
      "size": 790987, 
      "links": {
        "self": "https://rodare.hzdr.de/api/files/578725c9-1f4e-4ef3-8385-5ff8181142e2/06_%20radio-SEC-chromatogram_64Cu-L3-anti-FAP-TM_urine_1h.xlsx"
      }, 
      "bucket": "578725c9-1f4e-4ef3-8385-5ff8181142e2", 
      "type": "xlsx", 
      "checksum": "md5:f4721cbcde8487cb78a1a49067c9e32d"
    }, 
    {
      "key": "07_radio-SEC-chromatogram_64Cu-L1-anti-FAP-TM_urine_6h.xlsx", 
      "size": 788005, 
      "links": {
        "self": "https://rodare.hzdr.de/api/files/578725c9-1f4e-4ef3-8385-5ff8181142e2/07_radio-SEC-chromatogram_64Cu-L1-anti-FAP-TM_urine_6h.xlsx"
      }, 
      "bucket": "578725c9-1f4e-4ef3-8385-5ff8181142e2", 
      "type": "xlsx", 
      "checksum": "md5:2f07e0dbad81c3b48ab1301621c46ffe"
    }, 
    {
      "key": "08_radio-SEC-chroamtogram_64Cu-L3-anti-FAP-TM_urine_6h.xlsx", 
      "size": 786297, 
      "links": {
        "self": "https://rodare.hzdr.de/api/files/578725c9-1f4e-4ef3-8385-5ff8181142e2/08_radio-SEC-chroamtogram_64Cu-L3-anti-FAP-TM_urine_6h.xlsx"
      }, 
      "bucket": "578725c9-1f4e-4ef3-8385-5ff8181142e2", 
      "type": "xlsx", 
      "checksum": "md5:1ed7efc5a8f56e72dd2a2bc847aff5c2"
    }, 
    {
      "key": "09_radio-SEC_chromatogram_64Cu-L1-anti-FAP-TM_blood_1h.xlsx", 
      "size": 727262, 
      "links": {
        "self": "https://rodare.hzdr.de/api/files/578725c9-1f4e-4ef3-8385-5ff8181142e2/09_radio-SEC_chromatogram_64Cu-L1-anti-FAP-TM_blood_1h.xlsx"
      }, 
      "bucket": "578725c9-1f4e-4ef3-8385-5ff8181142e2", 
      "type": "xlsx", 
      "checksum": "md5:21f8e54aae0e129d8190f96e314f5069"
    }, 
    {
      "key": "10_radio-SEC_chromatogram_64Cu-L3-anti-FAP-TM_blood_1h.xlsx", 
      "size": 702651, 
      "links": {
        "self": "https://rodare.hzdr.de/api/files/578725c9-1f4e-4ef3-8385-5ff8181142e2/10_radio-SEC_chromatogram_64Cu-L3-anti-FAP-TM_blood_1h.xlsx"
      }, 
      "bucket": "578725c9-1f4e-4ef3-8385-5ff8181142e2", 
      "type": "xlsx", 
      "checksum": "md5:457b9cfa8ffd77d7be37c6dc1222b173"
    }, 
    {
      "key": "11_radio-SEC-chroamtorgam_64Cu-L1-anti-FAP-TM_blood_6h.xlsx", 
      "size": 788285, 
      "links": {
        "self": "https://rodare.hzdr.de/api/files/578725c9-1f4e-4ef3-8385-5ff8181142e2/11_radio-SEC-chroamtorgam_64Cu-L1-anti-FAP-TM_blood_6h.xlsx"
      }, 
      "bucket": "578725c9-1f4e-4ef3-8385-5ff8181142e2", 
      "type": "xlsx", 
      "checksum": "md5:f6bafc42b38eeffc6137c1959acc2b62"
    }, 
    {
      "key": "12_radio-SEC-chroamtogram_64Cu_L3-anti-FAP-TM_blood_6h.xlsx", 
      "size": 692774, 
      "links": {
        "self": "https://rodare.hzdr.de/api/files/578725c9-1f4e-4ef3-8385-5ff8181142e2/12_radio-SEC-chroamtogram_64Cu_L3-anti-FAP-TM_blood_6h.xlsx"
      }, 
      "bucket": "578725c9-1f4e-4ef3-8385-5ff8181142e2", 
      "type": "xlsx", 
      "checksum": "md5:a37869eaa9cf0060e0b5eb1a66429453"
    }, 
    {
      "key": "13_radio-SEC-chroamtogram_64Cu-L1-anti-FAP-TM_liver_1h.xlsx", 
      "size": 472473, 
      "links": {
        "self": "https://rodare.hzdr.de/api/files/578725c9-1f4e-4ef3-8385-5ff8181142e2/13_radio-SEC-chroamtogram_64Cu-L1-anti-FAP-TM_liver_1h.xlsx"
      }, 
      "bucket": "578725c9-1f4e-4ef3-8385-5ff8181142e2", 
      "type": "xlsx", 
      "checksum": "md5:e7c7033a6fb332f8e5bdc5028e42d0a1"
    }, 
    {
      "key": "14_radio-SEC-chromatogram_64Cu-L3-anti-FAP-TM_liver_1h.xlsx", 
      "size": 727994, 
      "links": {
        "self": "https://rodare.hzdr.de/api/files/578725c9-1f4e-4ef3-8385-5ff8181142e2/14_radio-SEC-chromatogram_64Cu-L3-anti-FAP-TM_liver_1h.xlsx"
      }, 
      "bucket": "578725c9-1f4e-4ef3-8385-5ff8181142e2", 
      "type": "xlsx", 
      "checksum": "md5:8a8968f0ebdac03b597856b5720dec87"
    }, 
    {
      "key": "15_radio-SEC-chroamtogram_64Cu-L1-anti-FAP-TM_liver_6h.xlsx", 
      "size": 783314, 
      "links": {
        "self": "https://rodare.hzdr.de/api/files/578725c9-1f4e-4ef3-8385-5ff8181142e2/15_radio-SEC-chroamtogram_64Cu-L1-anti-FAP-TM_liver_6h.xlsx"
      }, 
      "bucket": "578725c9-1f4e-4ef3-8385-5ff8181142e2", 
      "type": "xlsx", 
      "checksum": "md5:c573eec8092d71e3c8c524a707d14559"
    }, 
    {
      "key": "16_radio-SEC-chromatogram_64Cu-L3-anti-FAP-TM_liver_6h.xlsx", 
      "size": 785959, 
      "links": {
        "self": "https://rodare.hzdr.de/api/files/578725c9-1f4e-4ef3-8385-5ff8181142e2/16_radio-SEC-chromatogram_64Cu-L3-anti-FAP-TM_liver_6h.xlsx"
      }, 
      "bucket": "578725c9-1f4e-4ef3-8385-5ff8181142e2", 
      "type": "xlsx", 
      "checksum": "md5:5cca06e86e8c67aba783a2f08a5068c7"
    }, 
    {
      "key": "17_radio-SEC-chromatogram_64Cu-L3-anti-FAP-TM_tumor_1h.xlsx", 
      "size": 317769, 
      "links": {
        "self": "https://rodare.hzdr.de/api/files/578725c9-1f4e-4ef3-8385-5ff8181142e2/17_radio-SEC-chromatogram_64Cu-L3-anti-FAP-TM_tumor_1h.xlsx"
      }, 
      "bucket": "578725c9-1f4e-4ef3-8385-5ff8181142e2", 
      "type": "xlsx", 
      "checksum": "md5:a91e5b96722b78a4e6143766c409cf78"
    }, 
    {
      "key": "18_radio-SEC-chromatogram_64Cu-L1-anti-FAP-TM_tumor_6h.xlsx", 
      "size": 785884, 
      "links": {
        "self": "https://rodare.hzdr.de/api/files/578725c9-1f4e-4ef3-8385-5ff8181142e2/18_radio-SEC-chromatogram_64Cu-L1-anti-FAP-TM_tumor_6h.xlsx"
      }, 
      "bucket": "578725c9-1f4e-4ef3-8385-5ff8181142e2", 
      "type": "xlsx", 
      "checksum": "md5:f344a3d7cde257ee21fcfcfa9f41fd93"
    }, 
    {
      "key": "19_radio-SEC-chromatogram_64Cu-L3-anti-FAP-TM_tumor_6h.xlsx", 
      "size": 820446, 
      "links": {
        "self": "https://rodare.hzdr.de/api/files/578725c9-1f4e-4ef3-8385-5ff8181142e2/19_radio-SEC-chromatogram_64Cu-L3-anti-FAP-TM_tumor_6h.xlsx"
      }, 
      "bucket": "578725c9-1f4e-4ef3-8385-5ff8181142e2", 
      "type": "xlsx", 
      "checksum": "md5:f209e660cead045746c3d9d2812bf9eb"
    }, 
    {
      "key": "20_radio-SEC-chromatogram_64Cu-L1.xlsx", 
      "size": 465335, 
      "links": {
        "self": "https://rodare.hzdr.de/api/files/578725c9-1f4e-4ef3-8385-5ff8181142e2/20_radio-SEC-chromatogram_64Cu-L1.xlsx"
      }, 
      "bucket": "578725c9-1f4e-4ef3-8385-5ff8181142e2", 
      "type": "xlsx", 
      "checksum": "md5:d6a8d7b52af505c58cae0fbd7cacdc0c"
    }, 
    {
      "key": "21_radio-SEC-chroamtogram_64Cu-L3.xlsx", 
      "size": 476466, 
      "links": {
        "self": "https://rodare.hzdr.de/api/files/578725c9-1f4e-4ef3-8385-5ff8181142e2/21_radio-SEC-chroamtogram_64Cu-L3.xlsx"
      }, 
      "bucket": "578725c9-1f4e-4ef3-8385-5ff8181142e2", 
      "type": "xlsx", 
      "checksum": "md5:b076150316c158f298bff12f4d458261"
    }, 
    {
      "key": "Wizard_Gamma_counter_sattuartion_binding_64Cu_labelled_conjugates.xlsx", 
      "size": 22524, 
      "links": {
        "self": "https://rodare.hzdr.de/api/files/578725c9-1f4e-4ef3-8385-5ff8181142e2/Wizard_Gamma_counter_sattuartion_binding_64Cu_labelled_conjugates.xlsx"
      }, 
      "bucket": "578725c9-1f4e-4ef3-8385-5ff8181142e2", 
      "type": "xlsx", 
      "checksum": "md5:91e8d9d3587fbf9f241371ff81e62207"
    }
  ], 
  "created": "2026-09-06T10:42:34.344566+00:00", 
  "revision": 4, 
  "conceptdoi": "10.14278/rodare.4992", 
  "conceptrecid": "4992", 
  "doi": "10.14278/rodare.4993"
}
1
1
views
downloads
All versions This version
Views 11
Downloads 11
Data volume 355.2 kB355.2 kB
Unique views 11
Unique downloads 11
More info on how stats are collected.
Publication date:
September 3, 2026
DOI:
10.14278/rodare.4993

RODARE DOI Badge

DOI 

10.14278/rodare.4993

Markdown 

[![DOI](https://rodare.hzdr.de/badge/DOI/10.14278/rodare.4993.svg)](https://doi.org/10.14278/rodare.4993)

reStructedText 

.. image:: https://rodare.hzdr.de/badge/DOI/10.14278/rodare.4993.svg
   :target: https://doi.org/10.14278/rodare.4993

HTML 

<a href="https://doi.org/10.14278/rodare.4993"><img src="https://rodare.hzdr.de/badge/DOI/10.14278/rodare.4993.svg" alt="DOI"></a>

Image URL 

https://rodare.hzdr.de/badge/DOI/10.14278/rodare.4993.svg

Target URL 

https://doi.org/10.14278/rodare.4993

Keyword(s):
bispidine chelators copper-64 radioimmunoconjugate fibroblast activation protein positron emission tomography
Related identifiers:
Identical to:
https://www.hzdr.de/publications/Publ-43869
Referenced by:
https://www.hzdr.de/publications/Publ-43868
Communities:
License (for files):
Creative Commons Attribution 4.0 International

Versions

Version 1 10.14278/rodare.4993 Sep 3, 2026
Cite all versions? You can cite all versions by using the DOI 10.14278/rodare.4992. This DOI represents all versions, and will always resolve to the latest one. Read more.

Share

Cite as

Export