Software Open Access

LyROI – nnU-Net-based Lymphoma Total Metabolic Tumor Volume Segmentation

Nikulin, Pavel; Hoberück, Sebastian; Apostolova, Ivayla; Maus, Jens; Hüttmann, Andreas; Dührsen, Ulrich; Kroschinsky, Frank; Kotzerke, Jörg; von Bonin, Malte; Bundschuh, Ralph; Braune, Anja; Hofheinz, Frank

MARC21 XML Export

<?xml version='1.0' encoding='UTF-8'?>
<record xmlns="http://www.loc.gov/MARC21/slim">
  <leader>00000nmm##2200000uu#4500</leader>
  <datafield tag="245" ind1=" " ind2=" ">
    <subfield code="a">LyROI – nnU-Net-based Lymphoma Total Metabolic Tumor Volume Segmentation</subfield>
  </datafield>
  <controlfield tag="001">4177</controlfield>
  <datafield tag="909" ind1="C" ind2="O">
    <subfield code="o">oai:rodare.hzdr.de:4177</subfield>
    <subfield code="p">software</subfield>
    <subfield code="p">software</subfield>
    <subfield code="p">user-health</subfield>
    <subfield code="p">user-pet-center</subfield>
    <subfield code="p">user-rodare</subfield>
    <subfield code="p">user-zrt</subfield>
  </datafield>
  <datafield tag="100" ind1=" " ind2=" ">
    <subfield code="a">Nikulin, Pavel</subfield>
    <subfield code="u">Department of Positron Emission Tomography, Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, Dresden, Germany</subfield>
    <subfield code="0">(orcid)0000-0002-4568-4018</subfield>
  </datafield>
  <datafield tag="024" ind1=" " ind2=" ">
    <subfield code="a">10.14278/rodare.4177</subfield>
    <subfield code="2">doi</subfield>
  </datafield>
  <datafield tag="700" ind1=" " ind2=" ">
    <subfield code="a">Hoberück, Sebastian</subfield>
    <subfield code="u">Department of Nuclear Medicine, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany</subfield>
  </datafield>
  <datafield tag="700" ind1=" " ind2=" ">
    <subfield code="a">Apostolova, Ivayla</subfield>
    <subfield code="u">Department for Diagnostic and Interventional Radiology and Nuclear Medicine, University Hospital Hamburg-Eppendorf, Hamburg, Germany</subfield>
  </datafield>
  <datafield tag="700" ind1=" " ind2=" ">
    <subfield code="a">Maus, Jens</subfield>
    <subfield code="u">Department of Positron Emission Tomography, Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, Dresden, Germany</subfield>
    <subfield code="0">(orcid)0000-0002-7195-9927</subfield>
  </datafield>
  <datafield tag="700" ind1=" " ind2=" ">
    <subfield code="a">Hüttmann, Andreas</subfield>
    <subfield code="u">Department of Hematology, West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany</subfield>
  </datafield>
  <datafield tag="700" ind1=" " ind2=" ">
    <subfield code="a">Dührsen, Ulrich</subfield>
    <subfield code="u">Department of Hematology, West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany</subfield>
  </datafield>
  <datafield tag="700" ind1=" " ind2=" ">
    <subfield code="a">Kroschinsky, Frank</subfield>
    <subfield code="u">Medical Department I, Dresden University Hospital, Dresden, Germany</subfield>
  </datafield>
  <datafield tag="700" ind1=" " ind2=" ">
    <subfield code="a">Kotzerke, Jörg</subfield>
    <subfield code="u">Department of Nuclear Medicine, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany</subfield>
  </datafield>
  <datafield tag="700" ind1=" " ind2=" ">
    <subfield code="a">von Bonin, Malte</subfield>
    <subfield code="u">Medical Department I, Dresden University Hospital, Dresden, Germany</subfield>
  </datafield>
  <datafield tag="700" ind1=" " ind2=" ">
    <subfield code="a">Bundschuh, Ralph</subfield>
    <subfield code="u">Department of Nuclear Medicine, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany</subfield>
  </datafield>
  <datafield tag="700" ind1=" " ind2=" ">
    <subfield code="a">Braune, Anja</subfield>
    <subfield code="u">Department of Positron Emission Tomography, Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, Dresden, Germany</subfield>
    <subfield code="0">(orcid)0000-0001-7707-9413</subfield>
  </datafield>
  <datafield tag="700" ind1=" " ind2=" ">
    <subfield code="a">Hofheinz, Frank</subfield>
    <subfield code="u">Department of Positron Emission Tomography, Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, Dresden, Germany</subfield>
    <subfield code="0">(orcid)0000-0001-8016-4643</subfield>
  </datafield>
  <datafield tag="980" ind1=" " ind2=" ">
    <subfield code="a">software</subfield>
  </datafield>
  <datafield tag="650" ind1="1" ind2="7">
    <subfield code="a">cc-by</subfield>
    <subfield code="2">opendefinition.org</subfield>
  </datafield>
  <controlfield tag="005">20251212150505.0</controlfield>
  <datafield tag="520" ind1=" " ind2=" ">
    <subfield code="a">&lt;p&gt;Collection of neural network models for metabolic tumor volume segmentation in (Non-Hodgkin) lymphoma patients in FDG-PET/CT images. Intended to use within nnU-Net deep learning framework. Trained with a total of 1192 [&lt;sup&gt;18&lt;/sup&gt;F]FDG-PET/CT scans from 716 patients with Non-Hodgkin&amp;nbsp;lymphoma participating in the &lt;a href="https://doi.org/10.1200/jco.2017.76.8093"&gt;PETAL&lt;/a&gt; trial.&lt;/p&gt;

&lt;p&gt;For installation and usage instructions, please visit &lt;a href="http://github.com/hzdr-MedImaging/LyROI"&gt;https://github.com/hzdr-MedImaging/LyROI&lt;/a&gt;&lt;/p&gt;

&lt;p&gt;Please cite&amp;nbsp;&lt;a href="https://www.nature.com/articles/s41592-020-01008-z"&gt;nnU-Net&lt;/a&gt;&amp;nbsp;and the respective paper when using LyROI.&lt;/p&gt;</subfield>
  </datafield>
  <datafield tag="653" ind1=" " ind2=" ">
    <subfield code="a">FDG PET</subfield>
  </datafield>
  <datafield tag="653" ind1=" " ind2=" ">
    <subfield code="a">Total Metabolic Tumor Volume</subfield>
  </datafield>
  <datafield tag="653" ind1=" " ind2=" ">
    <subfield code="a">TMTV</subfield>
  </datafield>
  <datafield tag="653" ind1=" " ind2=" ">
    <subfield code="a">Non-Hodgkin Lymphoma</subfield>
  </datafield>
  <datafield tag="653" ind1=" " ind2=" ">
    <subfield code="a">Convolutional Neural Network</subfield>
  </datafield>
  <datafield tag="653" ind1=" " ind2=" ">
    <subfield code="a">Delineation</subfield>
  </datafield>
  <datafield tag="260" ind1=" " ind2=" ">
    <subfield code="c">2025-11-26</subfield>
  </datafield>
  <datafield tag="856" ind1="4" ind2=" ">
    <subfield code="s">1148064359</subfield>
    <subfield code="u">https://rodare.hzdr.de/record/4177/files/LyROI_Orig.zip</subfield>
    <subfield code="z">md5:af57366f934b5ddee335c7e41890b5e3</subfield>
  </datafield>
  <datafield tag="856" ind1="4" ind2=" ">
    <subfield code="s">3822206569</subfield>
    <subfield code="u">https://rodare.hzdr.de/record/4177/files/LyROI_ResL.zip</subfield>
    <subfield code="z">md5:1bac0c45826c054d691ae7ee309cdb4a</subfield>
  </datafield>
  <datafield tag="856" ind1="4" ind2=" ">
    <subfield code="s">3799358334</subfield>
    <subfield code="u">https://rodare.hzdr.de/record/4177/files/LyROI_ResM.zip</subfield>
    <subfield code="z">md5:a726321d41d2e835d781cb438b29edab</subfield>
  </datafield>
  <datafield tag="856" ind1="4" ind2=" ">
    <subfield code="s">23</subfield>
    <subfield code="u">https://rodare.hzdr.de/record/4177/files/VERSION</subfield>
    <subfield code="z">md5:3f74232ce9a4216c59b81b3d5aab57af</subfield>
  </datafield>
  <datafield tag="773" ind1=" " ind2=" ">
    <subfield code="a">https://www.hzdr.de/publications/Publ-42318</subfield>
    <subfield code="i">isIdenticalTo</subfield>
    <subfield code="n">url</subfield>
  </datafield>
  <datafield tag="773" ind1=" " ind2=" ">
    <subfield code="a">https://www.hzdr.de/publications/Publ-42236</subfield>
    <subfield code="i">isReferencedBy</subfield>
    <subfield code="n">url</subfield>
  </datafield>
  <datafield tag="773" ind1=" " ind2=" ">
    <subfield code="a">https://github.com/hzdr-MedImaging/LyROI</subfield>
    <subfield code="i">isSupplementTo</subfield>
    <subfield code="n">url</subfield>
  </datafield>
  <datafield tag="773" ind1=" " ind2=" ">
    <subfield code="a">10.14278/rodare.4160</subfield>
    <subfield code="i">isVersionOf</subfield>
    <subfield code="n">doi</subfield>
  </datafield>
  <datafield tag="980" ind1=" " ind2=" ">
    <subfield code="a">user-health</subfield>
  </datafield>
  <datafield tag="980" ind1=" " ind2=" ">
    <subfield code="a">user-pet-center</subfield>
  </datafield>
  <datafield tag="980" ind1=" " ind2=" ">
    <subfield code="a">user-rodare</subfield>
  </datafield>
  <datafield tag="980" ind1=" " ind2=" ">
    <subfield code="a">user-zrt</subfield>
  </datafield>
  <datafield tag="542" ind1=" " ind2=" ">
    <subfield code="l">open</subfield>
  </datafield>
  <datafield tag="540" ind1=" " ind2=" ">
    <subfield code="u">https://creativecommons.org/licenses/by-sa/4.0/legalcode</subfield>
    <subfield code="a">Creative Commons Attribution Share Alike 4.0 International</subfield>
  </datafield>
</record>
0
0
views
downloads
All versions This version
Views 00
Downloads 00
Data volume 0 Bytes0 Bytes
Unique views 00
Unique downloads 00
More info on how stats are collected.
Available in
Publication date:
November 26, 2025
DOI:
10.14278/rodare.4177

RODARE DOI Badge

DOI 

10.14278/rodare.4177

Markdown 

[![DOI](https://rodare.hzdr.de/badge/DOI/10.14278/rodare.4177.svg)](https://doi.org/10.14278/rodare.4177)

reStructedText 

.. image:: https://rodare.hzdr.de/badge/DOI/10.14278/rodare.4177.svg
   :target: https://doi.org/10.14278/rodare.4177

HTML 

<a href="https://doi.org/10.14278/rodare.4177"><img src="https://rodare.hzdr.de/badge/DOI/10.14278/rodare.4177.svg" alt="DOI"></a>

Image URL 

https://rodare.hzdr.de/badge/DOI/10.14278/rodare.4177.svg

Target URL 

https://doi.org/10.14278/rodare.4177

Keyword(s):
FDG PET Total Metabolic Tumor Volume TMTV Non-Hodgkin Lymphoma Convolutional Neural Network Delineation
Related identifiers:
Identical to:
https://www.hzdr.de/publications/Publ-42318
Referenced by:
https://www.hzdr.de/publications/Publ-42236
Supplement to:
https://github.com/hzdr-MedImaging/LyROI
Communities:
License (for files):
Creative Commons Attribution Share Alike 4.0 International

Versions

Version 1.0.1 10.14278/rodare.4177 Nov 26, 2025
Version 1.0.0 10.14278/rodare.4161 Nov 26, 2025
Cite all versions? You can cite all versions by using the DOI 10.14278/rodare.4160. This DOI represents all versions, and will always resolve to the latest one. Read more.

Share

Cite as

Export