Dataset Open Access

Slice2Volume: Fusion of multimodal medical imaging and light microscopy data of irradiation-injured brain tissue in 3D.

Müller, Johannes; Suckert, Theresa; Beyreuther, Elke; Schneider, Moritz; Boucsein, Marc; Bodenstein, Elisabeth; Stolz-Kieslich, Liane; Krause, Mechthild; Neubeck, Cläre Von; Haase, Robert; Lühr, Armin; Dietrich, Antje; Nexhipi, Sindi

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In particular, the image data comprise cone-bem computed tomographies (CBCT), Monte Carlo beam transport simulations based on those CTs, regular magnetic resonance imaging (MRI) follow-up (&amp;ge;&amp;nbsp;26 weeks), a co-aligned DSURQE mouse brain atlas&amp;nbsp;and scanned whole-brain tissue sections with histochemical and immunofluorescent markers for morphology (H&amp;amp;E), cell nuclei (DAPI), astrocytes (GFAP), microglia (Iba1), the intermediate filament protein Nestin, proliferation (Ki67), neurons (NeuN) and oligodendrocytes (OSP).&amp;nbsp;&amp;nbsp;&amp;nbsp;&amp;nbsp;&amp;nbsp;&amp;nbsp;&amp;nbsp;&amp;nbsp;&amp;nbsp;&amp;nbsp;&lt;br&gt;
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&lt;p&gt;&amp;nbsp;&lt;/p&gt;

&lt;p&gt;We provide the data in raw format and as aligned data sets, as well as their spatial transformations.&lt;/p&gt;</subfield>
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Publication date:
September 21, 2022
DOI:
10.14278/rodare.3131

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10.14278/rodare.3131

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Keyword(s):
Preclinical Image fusion Proton radiation Medical imaging Histology
Grants:
European Commission:
  • INSPIRE - INfraStructure in Proton International REsearch (730983)
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Has part:
https://www.hzdr.de/publications/Publ-32394
Cited by:
10.1016/j.radonc.2023.109591
Identical to:
https://www.hzdr.de/publications/Publ-32124
Referenced by:
10.3389/fonc.2020.598360, https://www.hzdr.de/publications/Publ-31469, https://www.hzdr.de/publications/Publ-32394
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Version 0.4.0 10.14278/rodare.3131 Sep 21, 2022
Version 0.3.1 10.14278/rodare.1849 Sep 21, 2022
Version 0.3.1 10.14278/rodare.915 Jan 20, 2021
Version 0.3 10.14278/rodare.810 Jan 20, 2021
Version 0.2.2 10.14278/rodare.801 Jan 20, 2021
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