2026-05-20T05:04:31Z https://rodare.hzdr.de/oai2d

oai:rodare.hzdr.de:3847 2025-07-18T07:52:59Z openaire_data user-rodare user-zrt

Anh Nguyen-Le, Trang Cela, Isli Feldmann, Anja Baek, Chang-Ki Bachmann, Michael Baraban, Larysa 2025-07-01 Collection of electrical measurements on an FET based biosensor. Electrical signal changes were measured upon exposure of modified Silicon nanowire semiconductor channel to WT and CAR T-cells. All electrical measurements were carried out on a microprobe station using a source-meter-unit (Keithley 2604B) controlled by a Matlab program. Measurements from different devices on two different chips are enclosed in the folder in Matlab readable files together with the processing script. Fluorescent Microscope images and video recordings of the cells on the sensor are also enclosed. https://rodare.hzdr.de/record/3847 10.14278/rodare.3847 oai:rodare.hzdr.de:3847 doi:10.1002/adsr.202500029 url:https://www.hzdr.de/publications/Publ-41578 url:https://www.hzdr.de/publications/Publ-41212 doi:10.14278/rodare.3846 url:https://rodare.hzdr.de/communities/rodare url:https://rodare.hzdr.de/communities/zrt info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by/4.0/legalcode biosensor CAR T-cell immunotherapy silicon nanowires GMP production Data publication: Label-free FET based biosensor for detection of engineered CAR T-cells at single cell resolution info:eu-repo/semantics/other dataset

oai:rodare.hzdr.de:4360 2026-01-12T06:47:21Z openaire_data user-rodare user-zrt user-health

Kogler, Jürgen Donat, Cornelius Trommer, Johanna Kopka, Klaus Stadlbauer, Sven 2025-11-19 Analytical data for chemical synthesis (HPLC, NMR, HRMS), biological data for in vitro and in vivo evaluation (binding assays, small animal imaging) https://rodare.hzdr.de/record/4360 10.14278/rodare.4360 oai:rodare.hzdr.de:4360 eng doi:10.1186/s41181-025-00398-9 url:https://www.hzdr.de/publications/Publ-42251 url:https://www.hzdr.de/publications/Publ-42101 doi:10.14278/rodare.4142 url:https://rodare.hzdr.de/communities/health url:https://rodare.hzdr.de/communities/rodare url:https://rodare.hzdr.de/communities/zrt info:eu-repo/semantics/restrictedAccess FAP FAPI PET fluorescence-guided surgery noninvasive molecular imaging Data publication: Synthesis and preclinical evaluation of FAP-targeting radiotracers for PET and optical imaging info:eu-repo/semantics/other dataset

oai:rodare.hzdr.de:4101 2025-11-12T07:07:09Z openaire_data user-rodare user-zrt

Craig, Austin Sachse, Frederik Laube, Markus Brandt, Florian Kopka, Klaus Stadlbauer, Sven 2025-11-10 This Dataset contains raw NMR spectra, IR spectra, (U)HPLC chromatograms and HRMS spectra of reported compounds. https://rodare.hzdr.de/record/4101 10.14278/rodare.4101 oai:rodare.hzdr.de:4101 doi:10.3390/pharmaceutics17070837 url:https://www.hzdr.de/publications/Publ-42159 doi:10.3390/pharmaceutics17070837 url:https://www.hzdr.de/publications/Publ-42091 doi:10.14278/rodare.4100 url:https://rodare.hzdr.de/communities/rodare url:https://rodare.hzdr.de/communities/zrt info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by/4.0/legalcode copper-mediated radiohalogenation (CMRH) ¹⁸F-fluorination ¹²³I-iodination positron emission tomography (PET) radiohalogenation single-photon emission computed tomography (SPECT) prosthetic group Data publication: PET and SPECT Tracer Development via Copper-Mediated Radiohalogenation of Divergent and Stable Aryl-Boronic Esters info:eu-repo/semantics/other dataset

oai:rodare.hzdr.de:2100 2024-08-14T13:26:29Z openaire_data user-rodare user-zrt

Cieslik, Patrick Kubeil, Manja Zarschler, Kristof Ullrich, Martin Brandt, Florian Anger, Karl Wadepohl, Hubert Kopka, Klaus Bachmann, Michael Pietzsch, Jens Stephan, Holger Comba, Peter 2023-01-25 Bei diesem Datensatz handelt es sich um analytische Charakterisierungen (ESI-MS, HR-MS, MALDI-TOF-MS) und Radiomarkierungsuntersuchungen zum nonadentaten Bispidin-Chelator bzw. Bispidin-TATE Konjugat mit Lutetium-177, Indium-111 und/oder Actinium-225. 1H, 13 C NMR and crystallographic data stored by collaboration partner (Heidelberg University) https://rodare.hzdr.de/record/2100 10.14278/rodare.2100 oai:rodare.hzdr.de:2100 doi:10.1021/jacs.2c08438 url:https://www.hzdr.de/publications/Publ-35458 url:https://www.hzdr.de/publications/Publ-35394 doi:10.14278/rodare.2099 url:https://rodare.hzdr.de/communities/rodare url:https://rodare.hzdr.de/communities/zrt info:eu-repo/semantics/closedAccess bispidine trivalent metal ions radionuclide theranostics somatostatin analogue actinium lutetium Data publication: One chelator for imaging and therapy with lutetium-177 and actinium-225 info:eu-repo/semantics/other dataset

oai:rodare.hzdr.de:4052 2025-10-23T11:20:12Z openaire_data user-rodare user-zrt

Burger, Eva-Maria Hill, Charlice Wodtke, Robert Zarschler, Kristof Laube, Markus Donat, Cornelius Hauser, Sandra Kopka, Klaus Pietzsch, Jens Stadlbauer, Sven 2025-10-23 This Dataset contains HPLC chromatograms and HRMS spectra of reported peptides. https://rodare.hzdr.de/record/4052 10.14278/rodare.4052 oai:rodare.hzdr.de:4052 eng url:https://www.hzdr.de/publications/Publ-42043 url:https://www.hzdr.de/publications/Publ-42042 doi:10.14278/rodare.4051 url:https://rodare.hzdr.de/communities/rodare url:https://rodare.hzdr.de/communities/zrt info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by/4.0/legalcode HCC GPC3 TJ12P2 Liver cancer Data publication: In vitro characterization of the published glypican 3 targeting peptide TJ12P2 reveals a lack of specificity and potency info:eu-repo/semantics/other dataset

oai:rodare.hzdr.de:3800 2025-06-12T11:59:56Z openaire_data openaire_data openaire_data openaire_data openaire_data openaire_data openaire_data openaire_data user-rodare user-zrt

Krutzek, Fabian Donat, Cornelius Stadlbauer, Sven 2025-06-10 Enthält NMR-, HR-MS- und HPLC-Rohdaten, sowie Bindungskinetiken und PET-Bilder von Kleintieren. https://rodare.hzdr.de/record/3800 10.14278/rodare.3800 oai:rodare.hzdr.de:3800 url:https://www.hzdr.de/publications/Publ-41453 url:https://www.hzdr.de/publications/Publ-41297 doi:10.14278/rodare.3799 url:https://rodare.hzdr.de/communities/rodare url:https://rodare.hzdr.de/communities/zrt info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by/4.0/legalcode PD-L1 radioligands positron emission tomography small molecules fluorine-18 chelators Data publication: Structure–Activity Relationship of 18F-Labeled PD-L1-Targeting Small Molecule Ligands: Impact of Radiolabeling Strategy on Affinity and In Vivo Performance info:eu-repo/semantics/other dataset

oai:rodare.hzdr.de:4161 2026-04-20T16:28:19Z software user-health user-pet-center user-rodare user-zrt

Nikulin, Pavel Hoberück, Sebastian Apostolova, Ivayla Maus, Jens Hüttmann, Andreas Dührsen, Ulrich Kroschinsky, Frank Kotzerke, Jörg von Bonin, Malte Bundschuh, Ralph Braune, Anja Hofheinz, Frank 2025-11-26 Collection of neural network models for metabolic tumor volume segmentation in (non-Hodgkin) lymphoma patients in FDG-PET/CT images. Intended to use within nnU-Net deep learning framework. For installation and usage instructions, please visit https://github.com/hzdr-MedImaging/LyROI https://rodare.hzdr.de/record/4161 10.14278/rodare.4161 oai:rodare.hzdr.de:4161 url:https://www.hzdr.de/publications/Publ-42318 url:https://www.hzdr.de/publications/Publ-42236 url:https://github.com/hzdr-MedImaging/LyROI doi:10.14278/rodare.4160 url:https://rodare.hzdr.de/communities/health url:https://rodare.hzdr.de/communities/pet-center url:https://rodare.hzdr.de/communities/rodare url:https://rodare.hzdr.de/communities/zrt info:eu-repo/semantics/closedAccess FDG PET Total Metabolic Tumor Volume TMTV Non-Hodgkin Lymphoma Convolutional Neural Network Delineation LyROI – nnU-Net-based Lymphoma Total Metabolic Tumor Volume Segmentation info:eu-repo/semantics/other software

oai:rodare.hzdr.de:4177 2026-04-20T16:28:19Z software software user-health user-pet-center user-rodare user-zrt

Nikulin, Pavel Hoberück, Sebastian Apostolova, Ivayla Maus, Jens Hüttmann, Andreas Dührsen, Ulrich Kroschinsky, Frank Kotzerke, Jörg von Bonin, Malte Bundschuh, Ralph Braune, Anja Hofheinz, Frank 2025-11-26 Collection of neural network models for metabolic tumor volume delineation in (Non-Hodgkin) lymphoma patients in FDG-PET/CT images. Intended to use within nnU-Net deep learning framework. Trained with a total of 1192 [18F]FDG-PET/CT scans from 716 patients with Non-Hodgkin lymphoma participating in the PETAL trial. For installation and usage instructions, please visit https://github.com/hzdr-MedImaging/LyROI Please cite nnU-Net and the respective paper when using LyROI. List of available models: LyROI_Orig.zip: regular U-Net LyROI_ResM.zip: residual encoder U-Net (medium) LyROI_ResL.zip: residual encoder U-Net (large) https://rodare.hzdr.de/record/4177 10.14278/rodare.4177 oai:rodare.hzdr.de:4177 url:https://www.hzdr.de/publications/Publ-42318 url:https://www.hzdr.de/publications/Publ-42236 url:https://github.com/hzdr-MedImaging/LyROI doi:10.14278/rodare.4160 url:https://rodare.hzdr.de/communities/health url:https://rodare.hzdr.de/communities/pet-center url:https://rodare.hzdr.de/communities/rodare url:https://rodare.hzdr.de/communities/zrt info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by-sa/4.0/legalcode FDG PET Total Metabolic Tumor Volume TMTV Non-Hodgkin Lymphoma Convolutional Neural Network Delineation LyROI – nnU-Net-based Lymphoma Total Metabolic Tumor Volume Delineation info:eu-repo/semantics/other software

oai:rodare.hzdr.de:2720 2024-08-14T12:27:05Z openaire_data user-casus user-matter user-rodare user-zrt

Martinetto, Vincent Shah, Karan Cangi, Attila Pribram-Jones, Aurora 2024-02-01 This data repository contains the datasets used in the paper "Inverting the Kohn-Sham equations with physics-informed machine learning". It contains the data generation scripts, datasets for the systems used in the paper (Single Well - 1D atom, Double Well - 1D diatomic molecule) and output potentials generated by the physics-informed machine learning models (physics-informed neural networks and Fourier neural operators). https://rodare.hzdr.de/record/2720 10.14278/rodare.2720 oai:rodare.hzdr.de:2720 doi:10.48550/arXiv.2312.15301 url:https://www.hzdr.de/publications/Publ-38725 doi:10.14278/rodare.2719 url:https://rodare.hzdr.de/communities/casus url:https://rodare.hzdr.de/communities/matter url:https://rodare.hzdr.de/communities/rodare url:https://rodare.hzdr.de/communities/zrt info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by/4.0/legalcode density functional theory machine learning Inverting the Kohn-Sham equations with physics-informed machine learning info:eu-repo/semantics/other dataset

oai:rodare.hzdr.de:3891 2025-08-14T11:58:22Z openaire_data user-rodare user-zrt

Brandt, Florian Ullrich, Martin Laube, Markus Löser, Reik Kotzerke, Jörg Kopka, Klaus Pietzsch, Jens van den Hoff, Jörg Wodtke, Robert 2025-07-29 Kd shift, binding and PET data https://rodare.hzdr.de/record/3891 10.14278/rodare.3891 oai:rodare.hzdr.de:3891 doi:10.1021/acs.jmedchem.5c00890 url:https://www.hzdr.de/publications/Publ-41661 url:https://www.hzdr.de/publications/Publ-40957 doi:10.14278/rodare.3890 url:https://rodare.hzdr.de/communities/rodare url:https://rodare.hzdr.de/communities/zrt info:eu-repo/semantics/closedAccess Data publication: Deciphering the tumor uptake of heterobivalent (SST₂/albumin) [⁶⁴Cu]Cu-NODAGA-cLAB-TATEs info:eu-repo/semantics/other dataset

oai:rodare.hzdr.de:4143 2026-01-12T06:47:21Z openaire_data user-rodare user-zrt user-health

Kogler, Jürgen Donat, Cornelius Trommer, Johanna Kopka, Klaus Stadlbauer, Sven 2025-11-19 Analytical data for chemical synthesis (HPLC, NMR, HRMS), biological data for in vitro and in vivo evaluation (binding assays, small animal imaging) https://rodare.hzdr.de/record/4143 10.14278/rodare.4143 oai:rodare.hzdr.de:4143 doi:10.1186/s41181-025-00398-9 url:https://www.hzdr.de/publications/Publ-42251 url:https://www.hzdr.de/publications/Publ-42101 doi:10.14278/rodare.4142 url:https://rodare.hzdr.de/communities/health url:https://rodare.hzdr.de/communities/rodare url:https://rodare.hzdr.de/communities/zrt info:eu-repo/semantics/restrictedAccess FAP FAPI PET fluorescence-guided surgery noninvasive molecular imaging Data publication: Synthesis and preclinical evaluation of FAP-targeting radiotracers for PET and optical imaging info:eu-repo/semantics/other dataset

oai:rodare.hzdr.de:2561 2024-08-14T12:37:47Z openaire_data user-rodare user-zrt

Craig, Austin Kogler, Jürgen Laube, Markus Ullrich, Martin Donat, Cornelius Wodtke, Robert Kopka, Klaus Stadlbauer, Sven 2023-11-17 The data concerns the preparation of two new 18F-labeled radiotracers using a ultra-fast radiolabeling method for tumor detection using positron emission tomography (PET) imaging. https://rodare.hzdr.de/record/2561 10.14278/rodare.2561 oai:rodare.hzdr.de:2561 url:https://www.hzdr.de/publications/Publ-37850 url:https://www.hzdr.de/publications/Publ-37644 doi:10.14278/rodare.2560 url:https://rodare.hzdr.de/communities/rodare url:https://rodare.hzdr.de/communities/zrt info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by/4.0/legalcode Automation cancer-associated fibroblast FAPI 18F-fluorination positron emission tomography (PET) [18F]SuFEx Data publication: Preparation of 18F-Labeled Tracers Targeting Fibroblast Activation Protein via Sulfur [18F]Fluoride Exchange Reaction info:eu-repo/semantics/other dataset

oai:rodare.hzdr.de:2342 2024-08-14T12:38:14Z openaire_data user-rodare user-zrt

Ullrich, Martin Brandt, Florian Löser, Reik Pietzsch, Jens Wodtke, Robert 2023-06-24 Saturation binding data https://rodare.hzdr.de/record/2342 10.14278/rodare.2342 oai:rodare.hzdr.de:2342 doi:10.1021/acsomega.3c02755 url:https://www.hzdr.de/publications/Publ-37151 url:https://www.hzdr.de/publications/Publ-36797 doi:10.14278/rodare.2341 url:https://rodare.hzdr.de/communities/rodare url:https://rodare.hzdr.de/communities/zrt info:eu-repo/semantics/closedAccess Data publication: Comparative saturation binding analysis of ⁶⁴Cu-labeled somatostatin analogs using cell homogenates and intact cells info:eu-repo/semantics/other dataset

oai:rodare.hzdr.de:4199 2026-01-07T15:21:39Z software user-health user-hzdr user-pet-center user-rodare user-zrt

Maus, Jens Nitschke, Janina Nikulin, Pavel Hofheinz, Frank Barth, Mareike Lemm, Sandy Richter, Lena Pietzsch, Jens Braune, Anja Ullrich, Martin 2026-01-07 Collection of neural network models for automatic image segmentation of microscopic tumor spheroids. Intended to be used with nnU-Net deep-learning framework. Trained and tested on a total of microscopic images of mouse pheochromocytoma (MPC) tumor cells. In addition to the trained network model, a PyQt5-based graphical user interface tool is provided. This tool provides a complete pipeline for handling microscopic spheroid image data, running deep-learning–based delineation, and curating results for continuous model improvement. For installation and usage instructions, please visit https://github.com/hzdr-MedImaging/pyMarAI Please cite nnU-Net and the respective paper when using pyMarAI. List of available model types: pyMarAI-1.0.0-ecat.zip: nnUNetv2 ready network (for ECAT7) pyMarAI-1.0.0-nifti.zip: nnUNetv2 ready network (for NIFTI) https://rodare.hzdr.de/record/4199 10.14278/rodare.4199 oai:rodare.hzdr.de:4199 url:https://www.hzdr.de/publications/Publ-42498 url:https://www.hzdr.de/publications/Publ-42497 url:https://github.com/hzdr-MedImaging/pyMarAI doi:10.14278/rodare.4198 url:https://rodare.hzdr.de/communities/health url:https://rodare.hzdr.de/communities/hzdr url:https://rodare.hzdr.de/communities/pet-center url:https://rodare.hzdr.de/communities/rodare url:https://rodare.hzdr.de/communities/zrt info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by-sa/4.0/legalcode Tumor Spheroid Imaging Radiopharmacological Treatment Response Assays Delineation Cancer Deep-Learning Artifical Intelligence Convolutional Neural Networks Network model pyMarAI: nnU-Net-based Tumor Spheroids Auto Delineation info:eu-repo/semantics/other software

oai:rodare.hzdr.de:4621 2026-04-20T18:10:40Z software user-health user-pet-center user-rodare user-zrt

Nikulin, Pavel Hoberück, Sebastian Apostolova, Ivayla Maus, Jens Hüttmann, Andreas Dührsen, Ulrich Kroschinsky, Frank Kotzerke, Jörg von Bonin, Malte Bundschuh, Ralph Braune, Anja Hofheinz, Frank 2025-11-26 Collection of neural network models for metabolic tumor volume delineation in (Non-Hodgkin) lymphoma patients in FDG-PET/CT images. Intended to use within nnU-Net deep learning framework. Trained with a total of 1192 [18F]FDG-PET/CT scans from 716 patients with Non-Hodgkin lymphoma participating in the PETAL trial. For installation and usage instructions, please visit https://github.com/hzdr-MedImaging/LyROI Please cite nnU-Net and the respective paper when using LyROI. List of models: PET/CT: LyROI_Orig.zip: regular U-Net LyROI_ResM.zip: residual encoder U-Net (medium) LyROI_ResL.zip: residual encoder U-Net (large) PET-only: LyROI_PET_Orig.zip: regular U-Net LyROI_PET_ResM.zip: residual encoder U-Net (medium) LyROI_PET_ResL.zip: residual encoder U-Net (large) https://rodare.hzdr.de/record/4621 10.14278/rodare.4621 oai:rodare.hzdr.de:4621 url:https://www.hzdr.de/publications/Publ-42318 url:https://www.hzdr.de/publications/Publ-42236 url:https://github.com/hzdr-MedImaging/LyROI doi:10.14278/rodare.4160 url:https://rodare.hzdr.de/communities/health url:https://rodare.hzdr.de/communities/pet-center url:https://rodare.hzdr.de/communities/rodare url:https://rodare.hzdr.de/communities/zrt info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by-sa/4.0/legalcode FDG PET Total Metabolic Tumor Volume TMTV Non-Hodgkin Lymphoma Convolutional Neural Network Delineation LyROI – nnU-Net-based Lymphoma Total Metabolic Tumor Volume Delineation info:eu-repo/semantics/other software